Expression Pattern of Neuronal Markers in PB-MSCs Treated by Growth Factors Noggin, bFGF and EGF

@inproceedings{Fazeli2015ExpressionPO,
  title={Expression Pattern of Neuronal Markers in PB-MSCs Treated by Growth Factors Noggin, bFGF and EGF},
  author={Zahra Fazeli and Sayyed Mohammad Hossein Ghaderian and Masoumeh Rajabibazl and Siamak Salami and Nader Vazifeh Shiran and Mir Davood Omrani},
  booktitle={International journal of molecular and cellular medicine},
  year={2015}
}
Mesenchymal stem cells (MSCs) have the ability to differentiate into neuronal like cells under appropriate culture condition. In this study, we investigated whether MSCs derived from human peripheral blood (PB-MSCs) can differentiate into neuronal like cells by synergic effect of the growth factors EGF, bFGF and Noggin. For this purpose, the expression of five neuronal markers (Nestin, β III tubulin, NFM, MAP2 and NSE) were evaluated in treated PB-MSCs by SYBR Green Real time PCR. The… CONTINUE READING

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