Expression Analysis of Taste Signal Transduction Molecules in the Fungiform and Circumvallate Papillae of the Rhesus Macaque, Macaca mulatta

@inproceedings{Ishimaru2012ExpressionAO,
  title={Expression Analysis of Taste Signal Transduction Molecules in the Fungiform and Circumvallate Papillae of the Rhesus Macaque, Macaca mulatta},
  author={Yoshiro Ishimaru and Miki Abe and Tomiko Asakura and Hiroo Imai and Keiko Abe},
  booktitle={PloS one},
  year={2012}
}
The molecular mechanisms of the mammalian gustatory system have been examined in many studies using rodents as model organisms. In this study, we examined the mRNA expression of molecules involved in taste signal transduction in the fungiform papillae (FuP) and circumvallate papillae (CvP) of the rhesus macaque, Macaca mulatta, using in situ hybridization. TAS1R1, TAS1R2, TAS2Rs, and PKD1L3 were exclusively expressed in different subsets of taste receptor cells (TRCs) in the FuP and CvP. This… CONTINUE READING
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