Expression, regulation and function of the homeobox gene empty spiracles in brain and ventral nerve cord development of Drosophila

@article{Hartmann2000ExpressionRA,
  title={Expression, regulation and function of the homeobox gene empty spiracles in brain and ventral nerve cord development of Drosophila},
  author={Beate Hartmann and Frank Hirth and Uwe Walldorf and Heinrich Reichert},
  journal={Mechanisms of Development},
  year={2000},
  volume={90},
  pages={143-153}
}
We analyse the role of the empty spiracles (ems) gene in embryonic brain and ventral nerve cord development. ems is differentially expressed in the neurectoderm of the anterior head versus the trunk region of early embryos. A distal enhancer region drives expression in the deutocerebral brain anlage and a proximal enhancer region drives expression in the VNC and tritocerebral brain anlage. Mutant analysis indicates that in the anterior brain ems is necessary for regionalized neurogenesis in the… CONTINUE READING

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