Expression, purification and characterization of the extracellular domain of human Flt3 ligand in Escherichia coli

@article{Zhao2009ExpressionPA,
  title={Expression, purification and characterization of the extracellular domain of human Flt3 ligand in Escherichia coli},
  author={Xingcheng Zhao and Ping Zhang and Qiang Liu and Fei He and Lei Feng and Hua Han},
  journal={Molecular Biology Reports},
  year={2009},
  volume={37},
  pages={2301-2307}
}
Fms-like tyrosine kinase 3 ligand (Flt3 ligand, FL) is a cytokine that affects the growth, survival and/or differentiation of hematopoietic cells through the activation of specific tyrosine kinase receptors, and is potentially useful for in vitro HSC amplification. To express the extracellular domain of human Flt3 ligand (hFLext) in Escherichia coli, we… CONTINUE READING