Expression, purification, crystallization and preliminary X-ray diffraction analysis of nurse shark β2-microglobulin.

Abstract

β(2)-Microglobulin (β(2)m) is an essential subunit of the major histocompatibility complex (MHC) class I molecule that helps to stabilize the structure of peptide-MHC I (pMHC I). It is also one of the typical immunoglobulin superfamily (IgSF) molecules in the adaptive immune system (AIS). Sharks belong to the cartilaginous fish, which are the oldest jawed… (More)
DOI: 10.1107/S1744309112006811

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