Expression, mitogenic activity and regulation by growth hormone of growth hormone/insulin-like growth factor in Branchiostoma belcheri

@article{Guo2009ExpressionMA,
  title={Expression, mitogenic activity and regulation by growth hormone of growth hormone/insulin-like growth factor in Branchiostoma belcheri},
  author={Bin Guo and S. Zhang and S. Wang and Yujun Liang},
  journal={Cell and Tissue Research},
  year={2009},
  volume={338},
  pages={67-77}
}
The growth hormone (GH)/insulin-like growth factor (IGF) axis is unique to all the vertebrate species but its evolutionary origin is ill-defined. We therefore cloned a cDNA encoding Branchiostoma belcheri IGF (BbIGF). BbIGF was expressed in a tissue-specific manner, with the most abundant expression in the hepatic caecum, the putative liver precursor. The recombinant BbIGF expressed in vitro showed mitogenic activity capable of stimulating cell proliferation in the flounder gill, a… Expand
15 Citations
Characterization of insulin-like peptides (ILPs) in the sea urchin Strongylocentrotus purpuratus: insights on the evolution of the insulin family.
[Hepatic caecum of amphioxus and origin of vertebrate liver].
Molecular and evolutionary aspects of the protochordate digestive system
Developmental cell-cell communication pathways in the cephalochordate amphioxus: actors and functions.
...
1
2
...

References

SHOWING 1-10 OF 43 REFERENCES
Cloning and expression of insulin-like growth factors I and II in the shi drum (Umbrina cirrosa).
Evolution of insulin-like growth factor (IGF) function: production and characterization of recombinant hagfish IGF.
Comparative endocrinology of the insulin-like growth factor-binding protein.
Ancient divergence of insulin and insulin-like growth factor.
Structure and expression of a chicken insulin-like growth factor I precursor.
Structure and expression of the insulin-like peptide receptor from amphioxus.
The branching of insulin-like growth factor 1 and insulin: an immunohistochemical analysis during phylogeny
The phylogeny of the insulin-like growth factors.
IGFs stimulate zebrafish cell proliferation by activating MAP kinase and PI3-kinase-signaling pathways.
...
1
2
3
4
5
...