Expression, function, and regulation of E-type prostaglandin receptors (EP3) in the nonischemic and ischemic pig heart.

@article{Hohlfeld1997ExpressionFA,
  title={Expression, function, and regulation of E-type prostaglandin receptors (EP3) in the nonischemic and ischemic pig heart.},
  author={Thomas Hohlfeld and T P Zucker and Joerg Meyer and Karsten Schroer},
  journal={Circulation research},
  year={1997},
  volume={81 5},
  pages={765-73}
}
The action of prostacyclin, prostaglandin E1 (PGE1), and their mimetics on myocardial function includes changes in contractility, electrophysiological properties, and protection from injury caused by transient myocardial ischemia. This study was undertaken to investigate the basic properties of myocardial E-type prostaglandin (EP) receptors. Ligand binding studies using an enriched preparation of sarcolemmal membranes prepared from pig hearts revealed a single class of binding sites for [3H… CONTINUE READING

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ProstaglandinsChemical structure ofAlprostadil
The action of prostacyclin , prostaglandin E1 ( PGE1 ) , and their mimetics on myocardial function includes changes in contractility , electrophysiological properties , and protection from injury caused by transient myocardial ischemia .
The action of prostacyclin , prostaglandin E1 ( PGE1 ) , and their mimetics on myocardial function includes changes in contractility , electrophysiological properties , and protection from injury caused by transient myocardial ischemia .
The action of prostacyclin , prostaglandin E1 ( PGE1 ) , and their mimetics on myocardial function includes changes in contractility , electrophysiological properties , and protection from injury caused by transient myocardial ischemia .
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