Exposure to the Contraceptive Progestin, Gestodene, Alters Reproductive Behavior, Arrests Egg Deposition, and Masculinizes Development in the Fathead Minnow (Pimephales promelas).

@article{Frankel2016ExposureTT,
  title={Exposure to the Contraceptive Progestin, Gestodene, Alters Reproductive Behavior, Arrests Egg Deposition, and Masculinizes Development in the Fathead Minnow (Pimephales promelas).},
  author={Tyler Edward Frankel and Michael T. Meyer and Dana W Kolpin and Amanda B Gillis and David A. Alvarez and Edward F. Orlando},
  journal={Environmental science & technology},
  year={2016},
  volume={50 11},
  pages={5991-9}
}
Endogenous progestogens and pharmaceutical progestins enter the environment through wastewater treatment plant effluent and agricultural field runoff. Lab studies demonstrate strong, negative exposure effects of these chemicals on aquatic vertebrate reproduction. Behavior can be a sensitive, early indicator of exposure to environmental contaminants associated with altered reproduction yet is rarely examined in ecotoxicology studies. Gestodene is a human contraceptive progestin and a potent… CONTINUE READING

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