Exposure to perflubron is associated with decreased Syk phosphorylation in human neutrophils.

@article{Fernandez2001ExposureTP,
  title={Exposure to perflubron is associated with decreased Syk phosphorylation in human neutrophils.},
  author={R Fernandez and Vidya J. Sarma and Ellen M. Younkin and Ronald B. Hirschl and Peter A Ward and John G. Younger},
  journal={Journal of applied physiology},
  year={2001},
  volume={91 5},
  pages={
          1941-7
        }
}
Liquid ventilation with perflubron is associated with reduced neutrophil recruitment into the lung during acute injury. Perflubron also reduces chemotactic responses, the respiratory burst, and cytokine production in neutrophils and in alveolar macrophages in vitro. In the current studies, the effect of perflubron on neutrophil chemotaxis to formyl-Met-Leu-Phe (fMLP) and phagocytosis of opsonized sheep erythrocytes (EA) correlated with decreased phosphorylation of Syk, an important… Expand
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