Exposure to paternal alcoholism does not predict development of alcohol-use disorders in offspring: evidence from an offspring-of-twins study.

@article{Duncan2006ExposureTP,
  title={Exposure to paternal alcoholism does not predict development of alcohol-use disorders in offspring: evidence from an offspring-of-twins study.},
  author={Alexis E. Duncan and Jeffrey F. Scherrer and Qiang Fu and Kathleen K Bucholz and A Christopher Heath and William R. True and Jon Randolph Haber and Donelle Howell and Theodore Jacob},
  journal={Journal of studies on alcohol},
  year={2006},
  volume={67 5},
  pages={649-56}
}
OBJECTIVE Using an offspring-of-twins design, we tested the hypothesis that exposure to paternal alcoholism during the child's first 12 years will increase offspring risk for subsequent alcohol-use disorders (AUD). METHOD Structured psychiatric interviews assessed history of psychiatric and substance-use disorders in Vietnam Era Twin Registry fathers (n = 512), their offspring (n = 877), and mothers of the offspring (n = 507). Exposure was defined as the fathers' endorsement of any Diagnostic… CONTINUE READING

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