Exposure to hexanal odor influences maternal behavior and induces neonatal death in Fyn tyrosine kinase-deficient mice

@article{HamaguchiHamada2004ExposureTH,
  title={Exposure to hexanal odor influences maternal behavior and induces neonatal death in Fyn tyrosine kinase-deficient mice},
  author={Kayoko Hamaguchi-Hamada and Chiaki Sanbo and Shun Hamada and Takeshi Yagi},
  journal={Neuroscience Research},
  year={2004},
  volume={48},
  pages={259-267}
}
Fyn-deficient pups born of Fyn-deficient parents die because they fail to suckle within 1-2 days after birth. Here we demonstrate that the neonatal death phenotype was influenced by the genetic background and an environmental odor. The odor of hexanal (C6-aldehyde) partially impaired mouse maternal behavior and induced the neonatal death of Fyn-deficient pups born of Fyn-deficient parents. This death phenotype was first observed in the breeding environment using autoclaved chips of Douglas fir… CONTINUE READING

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