Exposure to flaxseed and its purified lignan reduces bone strength in young but not older male rats.

@article{Ward2001ExposureTF,
  title={Exposure to flaxseed and its purified lignan reduces bone strength in young but not older male rats.},
  author={Wendy E Ward and Yvonne V. Yuan and Angela M W Cheung and Lilian U. Thompson},
  journal={Journal of toxicology and environmental health. Part A},
  year={2001},
  volume={63 1},
  pages={53-65}
}
Flaxseed is the richest source of the plant lignan secoisolariciresinol diglycoside (SDG), which is converted to the two major mammalian lignans, enterodiol (ED) and enterolactone (EL), by colonic bacteria. Because both ED and EL can produce biological effects similar to estrogen, exposure to lignans during early stages of development may adversely alter the normal development of bone in males since bone is a hormone-sensitive tissue. To determine whether early exposure to flaxseed or its… CONTINUE READING

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