Exposure to ethanol during gastrulation alters somatosensory-motor cortices and the underlying white matter in the macaque.

@article{Miller2007ExposureTE,
  title={Exposure to ethanol during gastrulation alters somatosensory-motor cortices and the underlying white matter in the macaque.},
  author={Michael A Miller},
  journal={Cerebral cortex},
  year={2007},
  volume={17 12},
  pages={2961-71}
}
The present study tests the hypothesis that a critical window for cortical development coincides with the period of neural stem cell proliferation (during the first 6 weeks of gestation), specifically, gastrulation (on embryonic day [E] 19 and E20). Pregnant female macaques were exposed to ethanol 1 day/week for 6 or 24 weeks such that it included E19 or E20 or a time before or after the time of gastrulation. Total forebrain size was increased in macaques exposed to ethanol on E19 or E20. Thus… CONTINUE READING