Exposure to UVB induces accumulation of LFA-1+ T cells and enhanced expression of the chemokine psoriasin in normal human skin.

@article{Nuzzo2000ExposureTU,
  title={Exposure to UVB induces accumulation of LFA-1+ T cells and enhanced expression of the chemokine psoriasin in normal human skin.},
  author={Sergio di Nuzzo and Regien M. R. Sylva-Steenland and Cornelis W Koomen and Menno A. de Rie and Pranab Kumar Das and Jan Dositheus Bos and Marcel B. M. Teunissen},
  journal={Photochemistry and photobiology},
  year={2000},
  volume={72 3},
  pages={374-82}
}
Normal human skin shows preferential (epi)dermal infiltration of CD4+ T cells upon acute UV exposure. To study the mechanism behind this feature we locally exposed healthy volunteers to doses of UV commonly encountered by the population. Expression of integrins on T cells and expression of adhesion molecules on dermal endothelial cells were quantitatively assessed by immunohistochemistry in situ. We also investigated the effects of ultraviolet-B (UVB) exposure on psoriasin and IL-16, two… CONTINUE READING

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