Exposure to ABO‐nonidentical blood associated with increased in‐hospital mortality in patients with group A blood

@article{Pai2016ExposureTA,
  title={Exposure to ABO‐nonidentical blood associated with increased in‐hospital mortality in patients with group A blood},
  author={Menaka Pai and Richard J. Cook and Rebecca Barty and John William Eikelboom and Ker-Ai Lee and Nancy M. Heddle},
  journal={Transfusion},
  year={2016},
  volume={56}
}
Transfusing ABO‐compatible blood avoids most acute hemolytic reactions, but donor units that are ABO compatible are not necessarily ABO identical. Emerging data have raised concerns that ABO‐nonidentical blood products lead to adverse outcomes. 
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References

SHOWING 1-10 OF 22 REFERENCES
An association of ABO non‐identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients
Background  Transfusion of ABO non‐identical plasma, platelets and cryoprecipitate is routine practice even though adverse effects can occur.
Providing ABO‐identical platelets and cryoprecipitate to (almost) all patients: approach, logistics, and associated decreases in transfusion reaction and red blood cell alloimmunization incidence
TLDR
This data indicates that transfusing only ABO‐identical components whenever feasible, regardless of outdating or logistic considerations, is a viable option for transfusing blood components to surgical patients.
Impact of ABO-identical vs ABO-compatible nonidentical plasma transfusion in trauma patients.
TLDR
Exposure to ABO-compatible plasma results in an increase in overall complications, in particular ARDS and sepsis, and there is a stepwise increase in the complication rate as exposure increases.
ABO-mismatched platelet transfusions: strategies to mitigate patient exposure to naturally occurring hemolytic antibodies.
The clinical implications of platelet transfusions associated with ABO or Rh(D) incompatibility.
TLDR
New clinical studies are needed to define clearly the current risk associated to ABO- and/or Rh(D)-incompatible platelet transfusions, and such defined risks would help establish the most cost effective measures to prevent the appearance of the potential complications related to platelet use.
BLOOD COMPONENTS: Meta‐analysis of clinical studies of the purported deleterious effects of “old” (versus “fresh”) red blood cells: are we at equipoise?
BACKGROUND: A meta‐analysis examined whether the available data support an adequate suspicion that transfusion of old red blood cells (RBCs) is associated with increased mortality, organ failure,
ABO‐mismatched platelet transfusions and clinical outcomes after cardiac surgery
TLDR
The decision to introduce the HNA nomenclature as well as to include HNA-5a was made by the majority of the members of the Granulocyte Antigen Working Party of the ISBT after long and intense discussions and should be respected to avoid confusion and misunderstandings in the future.
The impact of uncross-matched blood transfusion on the need for massive transfusion and mortality: analysis of 5,166 uncross-matched units.
TLDR
The requirement for uncross-matched blood during the acute resuscitation of trauma patients is an independent predictor of mortality and the need for massive transfusion.
Duration of red-cell storage and complications after cardiac surgery.
TLDR
In patients undergoing cardiac surgery, transfusion of red cells that had been stored for more than 2 weeks was associated with a significantly increased risk of postoperative complications as well as reduced short-term and long-term survival.
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