Exposure parameters necessary for delayed puberty and mammary gland development in Long-Evans rats exposed in utero to atrazine.

@article{Rayner2004ExposurePN,
  title={Exposure parameters necessary for delayed puberty and mammary gland development in Long-Evans rats exposed in utero to atrazine.},
  author={Jennifer L. Rayner and Carmen R. Wood and Suzanne E. Fenton},
  journal={Toxicology and applied pharmacology},
  year={2004},
  volume={195 1},
  pages={23-34}
}
Our studies suggested that prenatal exposure to the herbicide atrazine (ATR) could delay vaginal opening (VO) and mammary development in the offspring of Long-Evans (LE) rats. To evaluate ATR exposure parameters required for pubertal delays, including mammary gland development, we used cross-fostering to determine if effects were strictly dam-mediated (via milk) or a direct effect (transplacental) on the pups. Timed-pregnant LE rats (N = 20/treatment group) were gavaged on gestational days (GD… CONTINUE READING

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