Exposure of surfactant protein A to ozone in vitro and in vivo impairs its interactions with alveolar cells.

@article{Oosting1992ExposureOS,
  title={Exposure of surfactant protein A to ozone in vitro and in vivo impairs its interactions with alveolar cells.},
  author={Ronald S. Oosting and J Freek van Iwaarden and Leendert van Bree and Jan Verhoef and Lambert M G van Golde and Henk P Haagsman},
  journal={The American journal of physiology},
  year={1992},
  volume={262 1 Pt 1},
  pages={L63-8}
}
This study focused on the question of whether exposure of surfactant protein A (SP-A) to ozone affected properties of this protein that may be involved in regulating alveolar type II cell and alveolar macrophage functions. In vitro exposure of human or canine SP-A to ozone reduced the ability of this protein to inhibit phorbol-ester induced secretion of [3H… CONTINUE READING