Exposure of mouse colon to dietary bile acid supplement induces sessile adenomas.

@article{Payne2010ExposureOM,
  title={Exposure of mouse colon to dietary bile acid supplement induces sessile adenomas.},
  author={Claire Margaret Payne and Hana Holubec and Achyut K. Bhattacharyya and Carol L. Bernstein and Harris Bernstein},
  journal={Inflammatory bowel diseases},
  year={2010},
  volume={16 5},
  pages={729-30}
}
To the Editor: A high fat diet is a risk factor for the development of inflammatory bowel disease (IBD) and colon cancer in humans. Deoxycholic acid (DOC) is increased in the colonic contents in response to a high fat diet. Thus, frequent exposure of the colonic lumen to high levels of DOC may play a role in the natural course of development of IBD and… CONTINUE READING