Exposure of iron foundry workers to polycyclic aromatic hydrocarbons: benzo(a)pyrene-albumin adducts and 1-hydroxypyrene as biomarkers for exposure.

@article{Omland1994ExposureOI,
  title={Exposure of iron foundry workers to polycyclic aromatic hydrocarbons: benzo(a)pyrene-albumin adducts and 1-hydroxypyrene as biomarkers for exposure.},
  author={O Omland and David Lee Sherson and {\AA}se Marie Hansen and Torben Sigsgaard and Herman Autrup and Erik Overgaard},
  journal={Occupational and environmental medicine},
  year={1994},
  volume={51 8},
  pages={513-8}
}
Exposure to polycyclic aromatic hydrocarbons (PAHs) in foundry workers has been evaluated by determination of benzo(a)pyrene-serum albumin adducts and urinary 1-hydroxypyrene. Benzo(a)pyrene binding to albumin and 1-hydroxypyrene were quantitatively measured by enzyme linked immunosorbent assay (ELISA) and reverse phase high performance liquid chromatography (HPLC), respectively. 70 male foundry workers and 68 matched controls were investigated. High and low exposure groups were defined from… CONTINUE READING

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Determination of 1 - hydroxypyrene in urine by high pressure liquid chromatography

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Validation of high performance liquid chromatography / fluorescence detection method for the simultaneous quantification of fifteen polycyclic aromatic hydrocarbons

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