Exposure of Bacillus subtilis to mercury induces accumulation of shorter tRNA Cys species.

@article{Hernndez2013ExposureOB,
  title={Exposure of Bacillus subtilis to mercury induces accumulation of shorter tRNA Cys species.},
  author={Andr{\'e}s Cruz Hern{\'a}ndez and Emmanuel S{\'a}nchez Millan and Sergio de Jes{\'u}s Romero G{\'o}mez and Jos{\'e} Antonio Cervantes Ch{\'a}vez and Rocio Garcia Mart{\'i}nez and X{\'o}chitl Pastrana Mart{\'i}nez and Jackeline Lizzeta Arvizu G{\'o}mez and George H. Jones and Juan Campos Guill{\'e}n},
  journal={Metallomics : integrated biometal science},
  year={2013},
  volume={5 4},
  pages={398-403}
}
RNA processing is an essential pathway in the regulation of genetic expression in the cell. In this work, Bacillus subtilis was used to understand the effects of mercury on the mechanism of tRNA metabolism. The CVAAS (cold vapor atomic absorption spectroscopy) method revealed that from the addition of HgCl2 (0.75 μg ml(-1)) during the bacterial exponential phase, ca. 48% of the added mercury was taken up by the cells. This led to an immediate reduction in the rate of cell division. During this… CONTINUE READING