I'm not sure I get the point. If at least one of the theory's prime assumptions is false, then the whole theory falls apart. And if an experiment proves that a valid argument's conclusion is false, then it follows that at least one of that argument's assumptions must be false. It doesn't really matter which of the assumptions is false though. (Well, it does matter if you're trying to fix the theory. But if you're merely trying to falsify it, it doesn't matter.)