Explosive Expansion of βγ-Crystallin Genes in the Ancestral Vertebrate

@article{Kapp2010ExplosiveEO,
  title={Explosive Expansion of $\beta$$\gamma$-Crystallin Genes in the Ancestral Vertebrate},
  author={G. Kapp{\'e} and A. Purkiss and S. van Genesen and C. Slingsby and N. Lubsen},
  journal={Journal of Molecular Evolution},
  year={2010},
  volume={71},
  pages={219 - 230}
}
In jawed vertebrates, βγ-crystallins are restricted to the eye lens and thus excellent markers of lens evolution. These βγ-crystallins are four Greek key motifs/two domain proteins, whereas the urochordate βγ-crystallin has a single domain. To trace the origin of the vertebrate βγ-crystallin genes, we searched for homologues in the genomes of a jawless vertebrate (lamprey) and of a cephalochordate (lancelet). The lamprey genome contains orthologs of the gnathostome βB1-, βA2- and γN-crystallin… Expand
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