Exploring the role of sex steroids through studies of receptor deficient mice

  title={Exploring the role of sex steroids through studies of receptor deficient mice},
  author={John F. Couse and Kenneth S. Korach},
  journal={Journal of Molecular Medicine},
Decades of study have described a number roles fulfilled by the steroid hormones and their respective receptors in sexual differentiation and development, reproductive function and behavior, and more recently in the function and maintenance of non-reproductive organ systems, such as skeletal muscle, bone and coronary tissues. The biological effects of the steroid hormones are believed to be mediated in part by specific receptor proteins that demonstrated great specificity for their respective… 
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