Exploring the potential of immuno-oncology-based treatment for patients with non-small cell lung cancer.

@article{Heigener2015ExploringTP,
  title={Exploring the potential of immuno-oncology-based treatment for patients with non-small cell lung cancer.},
  author={David Felix Heigener and Martin Reck},
  journal={Expert review of anticancer therapy},
  year={2015},
  volume={15 1},
  pages={69-83}
}
Immune evasion is recognized as a key strategy for cancer survival and progression. With increased understanding of immune escape mechanisms, the development of immunotherapies to restore anti-tumor immune responses has flourished. Immuno-oncology (I-O) agents targeting checkpoints in the immune regulation cascade currently form the mainstay of approaches of cancer immunotherapy. Since initial success in melanoma, evidence for the notable effects of the I-O modality has been expanding, with… CONTINUE READING