Exploring the physiology and pathology of aging in the intestine of Drosophila melanogaster

@inproceedings{Jasper2015ExploringTP,
  title={Exploring the physiology and pathology of aging in the intestine of Drosophila melanogaster
},
  author={Heinrich Jasper},
  booktitle={Invertebrate reproduction & development},
  year={2015}
}
The gastrointestinal tract, due to its role as a digestive organ and as a barrier between the exterior and interior milieus, is critically impacted by dietary, environmental, and inflammatory conditions that influence health and lifespan. Work in flies is now uncovering the multifaceted molecular mechanisms that control homeostasis in this tissue, and establishing its central role in health and lifespan of metazoans. The Drosophila intestine has thus emerged as a productive, genetically… CONTINUE READING
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Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America • 2012
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