Exploring the midgut transcriptome of Phlebotomus papatasi: comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania major-infected sandflies

@article{RamalhoOrtigo2007ExploringTM,
  title={Exploring the midgut transcriptome of Phlebotomus papatasi: comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania major-infected sandflies},
  author={Marcelo Ramalho-Ortig{\~a}o and Ryan C. Jochim and Jennifer M. Anderson and Phillip G. Lawyer and Van My Pham and Shaden Kamhawi and Jesus G Valenzuela},
  journal={BMC Genomics},
  year={2007},
  volume={8},
  pages={300 - 300}
}
In sandflies, the blood meal is responsible for the induction of several physiologic processes that culminate in egg development and maturation. During blood feeding, infected sandflies are also able to transmit the parasite Leishmania to a suitable host. Many blood-induced molecules play significant roles during Leishmania development in the sandfly midgut, including parasite killing within the endoperitrophic space. In this work, we randomly sequenced transcripts from three distinct high… CONTINUE READING

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