Exploring the genetic basis of disease using RNA interference.

  title={Exploring the genetic basis of disease using RNA interference.},
  author={Stephan Kissler and Luk van Parijs},
  journal={Expert review of molecular diagnostics},
  volume={4 5},
Cancer and autoimmunity are polygenic diseases. In order to better understand the mechanisms of disease development and progression it is essential to uncover which genes are involved. Much has been learned from population studies in human patients by searching for polymorphic genetic loci associated with disease. In addition, animal models of tumor… CONTINUE READING