Exploring the connectivity between the cerebellum and motor cortex in humans.

  title={Exploring the connectivity between the cerebellum and motor cortex in humans.},
  author={Zafiris Jeff Daskalakis and Guillermo O. Paradiso and Bruce K. Christensen and Paul B. Fitzgerald and Carolyn A. Gunraj and Robert Chen},
  journal={The Journal of physiology},
  volume={557 Pt 2},
Animal studies have shown that cerebellar projections influence both excitatory and inhibitory neurones in the motor cortex but this connectivity has yet to be demonstrated in human subjects. In human subjects, magnetic or electrical stimulation of the cerebellum 5-7 ms before transcranial magnetic stimulation (TMS) of the motor cortex decreases the TMS-induced motor-evoked potential (MEP), indicating a cerebellar inhibition of the motor cortex (CBI). TMS also reveals inhibitory and excitatory… CONTINUE READING
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