Exploring the anthelmintic properties of Australian native shrubs with respect to their potential role in livestock grazing systems

@article{Kotze2009ExploringTA,
  title={Exploring the anthelmintic properties of Australian native shrubs with respect to their potential role in livestock grazing systems},
  author={Andrew C. Kotze and J. E. O'grady and Jason Emms and Andrew F. Toovey and S. Hughes and Peter J Jessop and M. R. Bennell and Philip E. Vercoe and Dean Kingsley Revell},
  journal={Parasitology},
  year={2009},
  volume={136},
  pages={1065 - 1080}
}
SUMMARY We measured in vitro anthelmintic activity in extracts from 85 species of Australian native shrub, with a view to identifying species able to provide a degree of worm control in grazing systems. Approximately 40% of the species showed significant activity in inhibiting development of Haemonchus contortus larvae. The most active extracts showed IC50 values of 60–300 μg/ml. Pre-incubation with polyvinylpolypyrrolidine removed the activity from some extracts, implicating tannins as the… 
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63 Citations

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The presence of plants which were both highly preferred by the sheep and showed in vitro anthelmintic activity indicates a potential to develop the species as an anthel mintic shrub through selection of shrub populations dominated by such plants.
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