Exploring the Schistosoma mansoni adult male transcriptome using RNA-seq.

@article{Almeida2012ExploringTS,
  title={Exploring the Schistosoma mansoni adult male transcriptome using RNA-seq.},
  author={Giulliana Tessarin e Almeida and Murilo S. Amaral and Felipe C{\'e}sar Ferrarezi Beckedorff and Joao Paulo Kitajima and Ricardo DeMarco and Sergio Verjovski-Almeida},
  journal={Experimental parasitology},
  year={2012},
  volume={132 1},
  pages={
          22-31
        }
}
Schistosoma mansoni is one of the agents of schistosomiasis, a chronic and debilitating disease. Here we present a transcriptome-wide characterization of adult S. mansoni males by high-throughput RNA-sequencing. We obtained 1,620,432 high-quality ESTs from a directional strand-specific cDNA library, resulting in a 26% higher coverage of genome bases than that of the public ESTs available at NCBI. With a 15×-deep coverage of transcribed genomic regions, our data were able to (i) confirm for the… CONTINUE READING
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