Exploring the Multifactorial Nature of Autism Through Computational Systems Biology: Calcium and the Rho GTPase RAC1 Under the Spotlight

@article{ZeidnChuli2013ExploringTM,
  title={Exploring the Multifactorial Nature of Autism Through Computational Systems Biology: Calcium and the Rho GTPase RAC1 Under the Spotlight},
  author={Fares Zeid{\'a}n-Chuli{\'a} and Jos{\'e} Luiz Rybarczyk-Filho and Alla Salmina and Ben-Hur Neves de Oliveira and Mami Noda and Jos{\'e} Cl{\'a}udio Fonseca Moreira},
  journal={NeuroMolecular Medicine},
  year={2013},
  volume={15},
  pages={364-383}
}
  • Fares Zeidán-Chuliá, José Luiz Rybarczyk-Filho, +3 authors José Cláudio Fonseca Moreira
  • Published 2013
  • Biology, Medicine
  • NeuroMolecular Medicine
  • Autism is a neurodevelopmental disorder characterized by impaired social interaction and communication accompanied with repetitive behavioral patterns and unusual stereotyped interests. Autism is considered a highly heterogeneous disorder with diverse putative causes and associated factors giving rise to variable ranges of symptomatology. Incidence seems to be increasing with time, while the underlying pathophysiological mechanisms remain virtually uncharacterized (or unknown). By systematic… CONTINUE READING

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