Exploring symbioses by single-cell genomics.

@article{Kamke2012ExploringSB,
  title={Exploring symbioses by single-cell genomics.},
  author={Janine Kamke and Kristina Bayer and Tanja Woyke and Ute Hentschel},
  journal={The Biological bulletin},
  year={2012},
  volume={223 1},
  pages={
          30-43
        }
}
Single-cell genomics has advanced the field of microbiology from the analysis of microbial metagenomes where information is "drowning in a sea of sequences," to recognizing each microbial cell as a separate and unique entity. Single-cell genomics employs Phi29 polymerase-mediated whole-genome amplification to yield microgram-range genomic DNA from single microbial cells. This method has now been applied to a handful of symbiotic systems, including bacterial symbionts of marine sponges, insects… CONTINUE READING
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