Exploring intercellular signaling by proteomic approaches.

@article{Tian2014ExploringIS,
  title={Exploring intercellular signaling by proteomic approaches.},
  author={Ruijun Tian},
  journal={Proteomics},
  year={2014},
  volume={14 4-5},
  pages={
          498-512
        }
}
Cells live in a close social context by having mutual communication with their local microenvironment. This complex intercellular communication activates dynamic signaling pathways and regulates specific cell fate. MS-based proteomics has been approved to be inevitable for characterizing dynamic protein expression and PTMs on a global scale. However, because of technical difficulties for targeting membrane receptors and secreted proteins, especially in a physiologically relevant manner… CONTINUE READING
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