Exploring genetic interactions and networks with yeast

  title={Exploring genetic interactions and networks with yeast},
  author={Charles Boone and Howard A Bussey and Brenda J. Andrews},
  journal={Nature Reviews Genetics},
The development and application of genetic tools and resources has enabled a partial genetic-interaction network for the yeast Saccharomyces cerevisiae to be compiled. Analysis of the network, which is ongoing, has already provided a clear picture of the nature and scale of the genetic interactions that robustly sustain biological systems, and how cellular buffering is achieved at the molecular level. Recent studies in yeast have begun to define general principles of genetic networks, and also… CONTINUE READING
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