Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization.

@article{Wilson1999ExploringDA,
  title={Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization.},
  author={M A Wilson and Joseph L. Derisi and H. H. Kristensen and Paul Imboden and Sangeeta Rane and Patrick O. Brown and Gary K. Schoolnik},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 22},
  pages={
          12833-8
        }
}
  • M. Wilson, J. Derisi, G. Schoolnik
  • Published 26 October 1999
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
Tuberculosis is a chronic infectious disease that is transmitted by cough-propelled droplets that carry the etiologic bacterium, Mycobacterium tuberculosis. Although currently available drugs kill most isolates of M. tuberculosis, strains resistant to each of these have emerged, and multiply resistant strains are increasingly widespread. The growing problem of drug resistance combined with a global incidence of seven million new cases per year underscore the urgent need for new antituberculosis… 

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