Exploring cell-based tolerance strategies for hand and face transplantation.

  title={Exploring cell-based tolerance strategies for hand and face transplantation.},
  author={Madeline L. Fryer and Johanna Grahammer and Saami Khalifian and Georg J. Furtm{\"u}ller and W. P. Andrew Lee and Giorgio Raimondi and Gerald Brandacher},
  journal={Expert review of clinical immunology},
  volume={11 11},
Broader clinical application of reconstructive hand and face transplantation is hindered by the need for lifelong immunosuppression for allograft maintenance. In this review, we summarize various cell-based approaches to tolerance induction currently under investigation in both clinical and pre-clinical models to alleviate the need for chronic… CONTINUE READING