Exploring buffer space for molecular interactions.

@article{Andersson1999ExploringBS,
  title={Exploring buffer space for molecular interactions.},
  author={Karl Andersson and Daphne Areskoug and Emilia Hardenborg},
  journal={Journal of molecular recognition : JMR},
  year={1999},
  volume={12 5},
  pages={310-5}
}
The interaction of two molecules binding to each other is described by two rate parameters, the association rate parameter k(a) and the dissociation rate parameter k(d). Under standardized conditions these kinetic parameters can be determined by analysis of their interaction in an affinity-based biosensor system, such as BIACORE(R) 3000. The association rate describes the collision frequency and the attraction between two molecules and the dissociation rate describes the stability of the… CONTINUE READING

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