Exploring QSARs of the interaction of flavonoids with GABA (A) receptor using MLR, ANN and SVM techniques.

Abstract

Quantitative Structure-Activity Relationship (QSAR) models for binding affinity constants (log Ki) of 78 flavonoid ligands towards the benzodiazepine site of GABA (A) receptor complex were calculated using the machine learning methods: artificial neural network (ANN) and support vector machine (SVM) techniques. The models obtained were compared with those… (More)
DOI: 10.3109/14756366.2013.839557

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Cite this paper

@article{Deeb2014ExploringQO, title={Exploring QSARs of the interaction of flavonoids with GABA (A) receptor using MLR, ANN and SVM techniques.}, author={Omar Deeb and Basheerulla Shaik and Vijay K. Agrawal}, journal={Journal of enzyme inhibition and medicinal chemistry}, year={2014}, volume={29 5}, pages={670-6} }