Corpus ID: 34617976

Explorer Mining housekeeping genes with a Naive Bayes classifier

  title={Explorer Mining housekeeping genes with a Naive Bayes classifier},
  author={L. D. Ferrari and Stuart Aitken},
Background: Traditionally, housekeeping and tissue specific genes have been classified using direct assay of mRNA presence across different tissues, but these experiments are costly and the results not easy to compare and reproduce. Results: In this work, a Naive Bayes classifier based only on physical and functional characteristics of genes already available in databases, like exon length and measures of chromatin compactness, has achieved a 97% success rate in classification of human… Expand

Tables from this paper


A compendium of gene expression in normal human tissues.
Human housekeeping genes are compact.
Large-scale analysis of the human and mouse transcriptomes
  • A. Su, M. Cooke, +11 authors J. Hogenesch
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2002
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues.
Evaluation of gene expression measurements from commercial microarray platforms.
Housekeeping enzymes as virulence factors for pathogens.
Selection for short introns in highly expressed genes