Explorer Detection of a functional hybrid receptor gamma c / GM-CSFR beta in human hematopoietic CD 34 ( + ) cells


A functional hybrid receptor associating the common γ chain (γc) with the granulocyte/macrophage colony-stimulating factor receptor β (GM-CSFRβ) chain is found in mobilized human peripheral blood (MPB) CD34 hematopoietic progenitors, SCF/Flt3-L primed cord blood (CB) precursors (CB CD34 /CD56 ), and CD34 myeloid cell lines, but not in normal natural killer… (More)

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