Exploration of tradeoffs in intensity-modulated radiotherapy.

  title={Exploration of tradeoffs in intensity-modulated radiotherapy.},
  author={David L. Craft and Tarek F Halabi and T. Bortfeld},
  journal={Physics in medicine and biology},
  volume={50 24},
The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and we apply it to explore the tradeoff between tumour dose homogeneity and critical structure sparing. We show that for two phantom and two clinical cases, a smooth (as opposed to… CONTINUE READING