Exploration of the relationship between the tumor burden and the concentration of vascular endothelial growth factor in liver-cancer-bearing animals using immunomagnetic reduction assay.

@article{Huang2011ExplorationOT,
  title={Exploration of the relationship between the tumor burden and the concentration of vascular endothelial growth factor in liver-cancer-bearing animals using immunomagnetic reduction assay.},
  author={K. W. Huang and Shiyu Y Yang and Chao Yuan Yu and J. J. Chieh and Che-Chuan Yang and Herng-Er Horng and Chin-Yih Hong and Hong-Chang Yang and Chau-Chung Wu},
  journal={Journal of biomedical nanotechnology},
  year={2011},
  volume={7 4},
  pages={535-41}
}
To achieve early-stage diagnosis, a high-sensitivity assay method is needed. As a biomarker, vascular endothelial growth factor (VEGF) has played a growing role in diagnosing and treating hepatocellular carcinoma (HCC). In this work, an immunomagnetic reduction (IMR) through bio-functionalized magnetic nanoparticles and a high-temperature superconducting-quantum-interference-device magnetometer were utilized for quantitative detection of low-concentration VEGF in serum from rats with HCC. The… CONTINUE READING
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