Exploration of supraspinal mechanisms in effects of spinal cord stimulation: role of the locus coeruleus.


The neurobiological mechanisms of spinal cord stimulation (SCS) when applied for neuropathic pain are still incompletely known. Previous research indicates that brainstem circuitry is pivotal for the SCS effect. The present study aims at exploring the possible contribution to the SCS effects of the pain controlling system emanating from the locus coeruleus… (More)
DOI: 10.1016/j.neuroscience.2013.09.006


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