Exploration of molecular interactions in cholesterol superlattices: effect of multibody interactions.

  title={Exploration of molecular interactions in cholesterol superlattices: effect of multibody interactions.},
  author={Juyang Huang},
  journal={Biophysical journal},
  volume={83 2},
Experimental evidences have indicated that cholesterol may adapt highly regular lateral distributions (i.e., superlattices) in a phospholipid bilayer. We investigated the formations of superlattices at cholesterol mole fraction of 0.154, 0.25, 0.40, and 0.5 using Monte Carlo simulation. We found that in general, conventional pairwise-additive interactions cannot produce superlattices. Instead, a multibody (nonpairwise) interaction is required. Cholesterol superlattice formation reveals that… CONTINUE READING

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