Exploration of liver cancer genomes

@article{Shibata2014ExplorationOL,
  title={Exploration of liver cancer genomes},
  author={T. Shibata and H. Aburatani},
  journal={Nature Reviews Gastroenterology &Hepatology},
  year={2014},
  volume={11},
  pages={340-349}
}
Liver cancer is the third leading cause of cancer-related death worldwide. Advances in sequencing technologies have enabled the examination of liver cancer genomes at high resolution; somatic mutations, structural alterations, HBV integration, RNA editing and retrotransposon changes have been comprehensively identified. Furthermore, integrated analyses of trans-omics data (genome, transcriptome and methylome data) have identified multiple critical genes and pathways implicated in… Expand
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