Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data.

@article{Carvalho2007ExplorationNA,
  title={Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data.},
  author={Benilton Carvalho and Henrik Bengtsson and Terence P. Speed and Rafael A. Irizarry},
  journal={Biostatistics},
  year={2007},
  volume={8 2},
  pages={485-99}
}
In most microarray technologies, a number of critical steps are required to convert raw intensity measurements into the data relied upon by data analysts, biologists, and clinicians. These data manipulations, referred to as preprocessing, can influence the quality of the ultimate measurements. In the last few years, the high-throughput measurement of gene expression is the most popular application of microarray technology. For this application, various groups have demonstrated that the use of… CONTINUE READING
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