Exploiting tumor epigenetics to improve oncolytic virotherapy

Abstract

Oncolytic viruses (OVs) comprise a versatile and multi-mechanistic therapeutic platform in the growing arsenal of anticancer biologics. These replicating therapeutics find favorable conditions in the tumor niche, characterized among others by increased metabolism, reduced anti-tumor/antiviral immunity, and disorganized vasculature. Through a self… (More)
DOI: 10.3389/fgene.2013.00184

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Cite this paper

@inproceedings{Forbes2013ExploitingTE, title={Exploiting tumor epigenetics to improve oncolytic virotherapy}, author={Nicole Elise Forbes and Hesham Abdelbary and Mathieu Lupien and John Cameron Bell and Jean-Simon Diallo}, booktitle={Front. Genet.}, year={2013} }