Exploiting the therapeutic potential of microRNAs in viral diseases: expectations and limitations.

@article{Hemida2010ExploitingTT,
  title={Exploiting the therapeutic potential of microRNAs in viral diseases: expectations and limitations.},
  author={Maged Gomaa Hemida and Xin Cynthia Ye and Simone Thair and Decheng Yang},
  journal={Molecular diagnosis & therapy},
  year={2010},
  volume={14 5},
  pages={
          271-82
        }
}
New therapeutic approaches are urgently needed for serious diseases, including cancer, cardiovascular diseases, viral infections, and others. A recent direction in drug development is the utilization of nucleic acid-based therapeutic molecules, such as antisense oligonucleotides, ribozymes, short interfering RNA (siRNA), and microRNA (miRNA). miRNAs are endogenous, short, non-coding RNA molecules. Some viruses encode their own miRNAs, which play pivotal roles in viral replication and immune… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Biogenesis, evolution and functional targets of microRNA-125a

  • Molecular Genetics and Genomics
  • 2013
VIEW 1 EXCERPT
CITES BACKGROUND