Exploiting the apicoplast: apicoplast-targeting drugs and malaria vaccine development.

@article{Low2017ExploitingTA,
  title={Exploiting the apicoplast: apicoplast-targeting drugs and malaria vaccine development.},
  author={Leanne M Low and Danielle I Stanisic and Michael F Good},
  journal={Microbes and infection},
  year={2017},
  volume={20 9-10},
  pages={
          477-483
        }
}
The apicoplast, a relic plastid found in most Apicomplexan parasites, is a notable drug target. Certain antibiotics elicit a delayed death phenotype by targeting this organelle. Here, we review apicoplast-targeting drugs and their targets, particularly those that cause delayed death, and highlight its potential uses in malaria vaccine development. 
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