Exploiting the antivirulence efficacy of an ajoene-ciprofloxacin combination against Pseudomonas aeruginosa biofilm associated murine acute pyelonephritis.

@article{Vadekeetil2016ExploitingTA,
  title={Exploiting the antivirulence efficacy of an ajoene-ciprofloxacin combination against Pseudomonas aeruginosa biofilm associated murine acute pyelonephritis.},
  author={Anitha Vadekeetil and Hina Saini and Sanjay Chhibber and Kusum Harjai},
  journal={Biofouling},
  year={2016},
  volume={32 4},
  pages={371-82}
}
The study investigated the in vitro, ex vivo and in vivo efficacy of ajoene and ciprofloxacin (CIP) alone and in combination against Pseudomonas aeruginosa biofilms and biofilm-associated murine acute pyelonephritis. The ajoene-CIP combination exhibited significant greater (p < 0.05) antimotility and biofilm inhibitory effects than those obtained when they… CONTINUE READING